2-Arachidonyl glyceryl ether

2-Arachidonyl glyceryl ether
Names
	IUPAC name 2-O-[(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetrae-1-yl]glycerol
	Systematic IUPAC name 2-{[(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraen-1-yl]oxy}propane-1,3-diol
	Other names 2-AGE, 2-arachidonylglyceryl ether, Noladin ether, Noladin
Identifiers
CAS Number	222723-55-9 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:75913 ;
ChEMBL	ChEMBL146346 ;
ChemSpider	4983515 ;
IUPHAR/BPS	5545;
PubChem CID	6483057;
UNII	0D295FLV8W ;
	InChI InChI=1S/C23H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26-23(21-24)22-25/h6-7,9-10,12-13,15-16,23-25H,2-5,8,11,14,17-22H2,1H3/b7-6-,10-9-,13-12-,16-15- Key: CUJUUWXZAQHCNC-DOFZRALJSA-N ; InChI=1/C23H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26-23(21-24)22-25/h6-7,9-10,12-13,15-16,23-25H,2-5,8,11,14,17-22H2,1H3/b7-6-,10-9-,13-12-,16-15- Key: CUJUUWXZAQHCNC-DOFZRALJBH;
	SMILES OCC(OCCCC\C=C/C/C=C\C\C=C/C\C=C/CCCCC)CO;
Properties
Chemical formula	C23H40O3
Molar mass	364.56 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

2-Arachidonyl glyceryl ether (2-AGE, Noladin ether) is a putative endocannabinoid discovered by Lumír Hanuš and colleagues at the Hebrew University of Jerusalem, Israel. It is an ether formed from the alcohol analog of arachidonic acid and glycerol. Its isolation from porcine brain and its structural elucidation and synthesis were described in 2001.^[1]

^ Hanus, L.; Abu-Lafi, S.; Fride, E.; Breuer, A.; Vogel, Z.; Shalev, D.; Kustanovich, I.; Mechoulam, R. (2001). "2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor". Proceedings of the National Academy of Sciences. 98 (7): 3662–3665. Bibcode:2001PNAS...98.3662H. doi:10.1073/pnas.061029898. PMC 31108. PMID 11259648.